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Whilst this exploratory analysis was underpowered, there was a significant reduction in response to twice-daily exenatide in carriers of p.S539W compared with non-carriers (-0.84%, 95%CI [-1.56, -0.12], p = 0.023), whilst directionally consistent there was no significant difference between carriers of p.D563G (-0.19%, 95% CI [-0.66, 0.27], p = 0.41)

So for a smaller employer like that that wants to offer it, these LSAs are a safer way to do it because you're capping going in, you're giving 'em $500, you're giving 'em a thousand dollars, whatever that is going in, what your worst case scenario is and you know how to budget that

This correlation can then be used to extrapolate the concentration of antigen in an unknown sample from a standard curve

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