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Besides, cAMP, along with IL-4, activates CCAAT/enhancer-binding protein (C/EBP) to induce the expression of M2 regulatory genes (such as arginase-1), thus reducing the expression of M1-related inflammatory factors and increasing the expression of M2-related anti-inflammatory mediators (such as FIZZ1) (117)

Yes, and this is common in clinical practice

Finally, we obtained the consistent results of the association of GLP-1 RAs and DR thoroughly by incorporating information from an observational study and an MR analysis

"Emerging Anabolic and Regenerative Peptides in Athletic Body Re-composition and Bodybuilding." Genesis Publishing (2025)