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24 They also found that a reduction in BMI of at least 5% improved disease control in obese RA patients without changing the RA treatment

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According to MHRA guidance, it should be used at the lowest effective dose for the shortest possible duration (usually up to 7 days), is contraindicated in those with cardiac conduction disorders or QT prolongation, and should be avoided with QT-prolonging or CYP3A4-inhibiting drugs