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Our analysis reveals that the projected internal rate of return (IRR) on late-stage pipeline assets rose for the third consecutive year in 2025 to 7.0 per cent, a 1.1 percentage point improvement from 2024 (see Figure 1)

Tolerability results have been consistent with the GLP-1 RA class with the majority of the adverse events being gastrointestinal-related and mostly mild in severity