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10.1016/j.neuro.2003.10.005 33 CrossgroveJ

Skelly et al., 1998)

315 Notably, although tenofovir disoproxil fumarate treatment can significantly alter the gut flora of HBV-infected individuals, it failed to fully restore it to a healthy state, and serum inflammatory cytokine concentrations did not improve significantly, suggesting that treatment duration may affect flora recovery and inflammation remission

Research has documented reduced fat mass, decreased adipocyte size, and shifts in adipose tissue gene expression patterns toward fat-mobilizing rather than fat-storing phenotypes