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Many women find they eat considerably less than before which is the point of the medication, but it creates a real risk of inadequate protein, iron, and zinc intake even when diet quality is good

29 Also, following the renal-focused study CREDENCE, canagliflozin has documented ability to slow progression of renal decline in patients with low baseline eGRF and persistent proteinuria

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most patients experience reduced appetite within 24-72 hours of drug administration. The early reduction of cravings takes days, but the maximum semaglutide effect is reached in 12-68 weeks with the combined effects of diet and exercise