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In the stomach lining, there are cells with proton pumps that play a key role in producing stomach acid

[2]Current Patent Assignee: NEW SOUTH INNOVATIONS - US2006/166208, 2006, A1 Location in patent: Page/Page column 16

A detailed medical history is essential to identify possible exclusions

Thus, due to the nature of the original diagnostic criteria for GHD, and the reticence to consider aging a disease per se, even though disease risk, incidence and severity can be attributed at least in part to declining activity of the GH neuroendcrine axis, the criteria for determining if secretagogue therapy is indicated as an intervention in aging, are less stringent than those promulgated by Endocrine Society guidelines