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KLOW is a combination research blend of four peptides studied for overlapping regenerative and cytoprotective pathways: GHK-Cu (50mg), the copper tripeptide associated in published work with collagen and elastin synthesis, antioxidant activity and broad gene-expression modulation
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For example, the compound 13 (racemic) is a very week IRAP inhibitor ( 14 with a 4-hydroxydiphenylmethane scaffold as a substitute for Tyr 2 is essentially inactive (Figure 4) ( 1 is essential and the proper orientation of the Tyr 2 side chain in space is critical for activity and IRAP inhibition while various alternations and topography at the C-terminal are more acceptable
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