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Why These Medications Help with PCOS Both Semaglutide and Tirzepatide are GLP-1 receptor agonists (Tirzepatide also targets GIP , making it a dual agonist), and they: Improve insulin sensitivity Support weight loss Lower inflammation Help regulate appetite and blood sugar Key Benefits for PCOS Patients Semaglutide and Tirzepatide offer a wide range of benefits for individuals with PCOS by addressing many of the conditions underlying drivers