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Tirzepatide liver-fat and body-composition MRI substudy SURPASS-3, relative liver-fat reduction -29.8/-39.6/-47.1% at 5/10/15 mg vs insulin degludec -11.2%: Gastaldelli Lancet D&E 2022

Strength available: 10mg

Managing Side Effects Proactively The most common early side effects nausea, constipation, and fatigue are manageable with the right habits and largely resolve after the first few dose escalations

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